Big Sur not Currently Supported
Unfortunately, it looks like the latest release of OSX 11 (Big Sur) has made breaking changes in relation to how the version of Mozilla Komodo is using works with the OSX SDK. We’re currently investigating the scope of this problem. At this time we advise that Komodo users remain on OSX 10.x.
There is a workaround here: Komodo and Big Sur (DO NOT UPGRADE)