ActiveState is currently watching Perl 6 intently after it's release to see how it's accepted by the community. Currently there is very little interest, or at least not enough interest for the company to invest in producing new builds for Perl 6.
Komodo is looking into adding limited Perl 6 support for version 11.
We're very interested in our community members who have taken on Perl 6 though. Could you share what you're using Perl 6 for?